Centre of Translational Research

The Centre of Translational Research (CBT) at the Centre of Postgraduate Medical Education (CMKP, Centrum Medyczne Kształcenia Podyplomowego) brings together CMKP units engaged in scientific research in biomedicine. Its primary goal is to identify directions and diagnostic and therapeutic solutions in clinical medicine. The research is founded on close collaboration between basic laboratories and CMKP clinics, enabling a two-way transfer of data: “from the patient’s bedside to the laboratory bench” and vice versa (referred to as “bench-to-bedside” and “bedside-to-bench”). Examples of research conducted by CBT include the identification of biomarkers and novel molecular targets for disease therapy. CBT relies on in vitro models (cell cultures), ex vivo studies (using clinical material), and in vivo investigations (based on animal models).

The research teams within CBT collaborate with other CMKP clinics and departments on jointly executed research projects.

The Centre of Translational Research (CBT) focuses on several key research areas:

  1. Biomarker Identification: CBT investigates and identifies biomarkers that can serve as indicators for various diseases. These biomarkers play a crucial role in early diagnosis, prognosis, and monitoring treatment responses.
  2. Novel Therapeutic Targets and Therapies: Researchers at CBT explore novel molecular targets and drugs for therapeutic interventions. By understanding the underlying mechanisms of diseases, they aim to develop targeted therapies that improve patient outcomes. They also analyze efficacy and mechanisms of novel drugs in treatment of human diseases.
  3. Collaboration with Clinical Units: CBT facilitates collaboration between basic science laboratories and clinical departments within CMKP. This two-way exchange of data ensures that research findings are directly applicable to patient care.
  4. In Vitro Studies: CBT utilizes in vitro models, such as cell cultures, to study disease processes, drug interactions, and potential treatments. These controlled experiments provide valuable insights into cellular behavior.
  5. Ex Vivo Investigations: Researchers analyze clinical material (such as tissue samples) ex vivo. These studies bridge the gap between laboratory research and real-world patient scenarios.
  6. In Vivo Research: CBT conducts studies using animal models to evaluate new therapies, test hypotheses, and understand disease progression. These in vivo experiments inform clinical decision-making.

The labs involved in CBT include:


Professor Agnieszka Piekiełko-Witkowska
e-mail: agnieszka.piekielko-witkowska@cmkp.edu.pl
tel.: 22 56 93 810

Are you interested in collaboration with CBT? Please contact:

Professor Monika Duda
e-mail: cbt@cmkp.edu.pl
tel.: 22 56 93 844